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Replacement purifier cartridges for the UltraPress are designed to last 300 cycles (40 gal. / 150L). Lifespan will decline when purifying water with high levels of silt, sediment or tannins. Cartridge press time increases towards the end of the cartridge lifespan; when press time reaches 25-30 seconds, the cartridge should be replaced. Cartridge continues to protect, even as press time increases.